Study changes picture of U.S. quake hazards

Publ.Date : Fri, 30 Jul 2010 08:01:21 -0400

U.S. nuclear front-runners begin to slow spending

Publ.Date : Fri, 30 Jul 2010 17:36:28 -0400

Rabbits grow their own joint replacements in study

Publ.Date : Thu, 29 Jul 2010 13:15:49 -0400

Canadian archeologists find lost ship in Arctic

Publ.Date : Wed, 28 Jul 2010 23:50:50 -0400

Some space shuttle workers get layoff notice

Publ.Date : Tue, 27 Jul 2010 16:02:53 -0400

Mental health experts ask: Will anyone be normal?

Publ.Date : Wed, 28 Jul 2010 14:07:12 -0400

Scientists inch towards finding "God particle"

Publ.Date : Wed, 28 Jul 2010 11:21:37 -0400

Iran aims to put man in space by 2019: Ahmadinejad

Publ.Date : Fri, 23 Jul 2010 13:49:33 -0400

Educated people cope better with dementia

Publ.Date : Mon, 26 Jul 2010 07:06:16 -0400

Russia to use space tech to develop energy sector

Publ.Date : Tue, 27 Jul 2010 05:33:16 -0400

Consortia and commodities

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Pharma embraces open source models

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New eyes on old drugs

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Genetic testing clamp down

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New tech transfer models gain traction with deal flow

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French IPO spate

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Industrial biotech to boom?

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Sequencing firms vie for diagnostics market, tiptoe round patents

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Merck ditches biogeneric

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Investors fight Charles River/WuXi merger

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Genzyme partners TJAB

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China's heparin billionaires

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Microcap public biotechs access new pool of VC funding

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Italian GM rebels

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Newsmaker: Agios Pharmaceuticals

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Drug pipeline: Q210

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Sunshine on conflicts

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Ask your doctor

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PeptideClassifier for protein inference and targeted quantitative proteomics

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Minimum information about a protein affinity reagent (MIAPAR)

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Guidelines for reporting the use of column chromatography in proteomics

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Guidelines for reporting the use of capillary electrophoresis in proteomics

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Guidelines for reporting the use of gel image informatics in proteomics

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The 20-year environmental safety record of GM trees

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The pros and cons of peptide-centric proteomics

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Proteomics retrenches

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Intellectual property, technology transfer and manufacture of low-cost HPV vaccines in India

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Recent patent applications in stem cells

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Paring down signaling complexity

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Inhibitors for E3 ubiquitin ligases

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Systematic phenotyping of mouse mutants

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Splicing by cell type

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A synthetic DNA transplant

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Antibiotic leads challenge conventional wisdom

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Research highlights

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Cloud computing and the DNA data race

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Proteomics: a pragmatic perspective

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Options and considerations when selecting a quantitative proteomics strategy

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Live attenuated influenza virus vaccines by computer-aided rational design

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Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli

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An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase

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Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase

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Engineered allosteric activation of kinases in living cells

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A mouse knockout library for secreted and transmembrane proteins

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Corrigendum: Safety signal dampens reception for mipomersen antisense

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Corrigendum: Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

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Erratum: US biodefense contracts continue to lure biotechs

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Erratum: Single base–resolution methylome of the silkworm reveals a sparse epigenomic map

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Erratum: Up for grabs

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Advancing the careers of life science professionals of Indian origin

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People

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Human embryonic stem cell research in the US: time for change?

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Forming the cell rear first: breaking cell symmetry to trigger directed cell migration

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Hold on tightly, let go lightly: myosin functions at adherens junctions

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Rab6 and myosin II at the cutting edge of membrane fission

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Tagging the dead: a bridging factor for Caenorhabditis elegans phagocyte receptors

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Nuclear transport receptor goes moonlighting

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Cytosolic FoxO1: alive and killing

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Research highlights

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Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex

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Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

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The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

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Interplay between Cdh1 and JNK activity during the cell cycle

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Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

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Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and RanGTP

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Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

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Human POGZ modulates dissociation of HP1α from mitotic chromosome arms through Aurora B activation

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Mechanosensitive gating of CFTR

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