One postdoctoral position funded for at least 3 years is available immediately in the Gruss-Lipper Biophotonics Center at Albert Einstein College of Medicine in New York for the study of nanoscale probing of eukaryotic gene expression. The project utilizes several single molecule techniques to visualize mega-Dalton size macromolecule transcription assemblies responsible for diverse cellular processes including stem cell differentiation, cell cycle arrest, and apoptosis. The experimental approach involves a number of advanced techniques including single molecule TIRF microscopy(spFRET and SHREC) and in vivo live cell imaging(PALM/STORM) along with in vitro biochemical analysis.

In addition, candidates will have the opportunity to work closely with cryo-electron microscopists here at the Biophotonics center to combine TIRF microscopy and 3D single particle Cryo-EM as a multi-pronged approach to determining the structure and function of these dynamic transcription complex assemblies. Candidates will also utilize the facilities and collaborate extensively with researchers at HHMI’s Janelia Farm Research Campus outside of Washington, D.C.

Qualified candidates should have recently obtained a Ph.D. with a strong background in TIRF microscopy, biophysics, or biochemistry. Applicants with computational/programming experiences will be strongly considered. The successful applicants will join the cutting-edge interdisciplinary, innovative, and collaborative research environment in the Gruss-Lipper Biophotonics Center that is dedicated to developing advanced techniques to address devastating disease-driven biological questions and therapeutic targets.

We are seeking outstanding candidates who are self-motivated, creative and career-oriented to join our research team. Einstein is an equal opportunity/affirmative action employer. The research environment at the Gruss-Lipper Biophotonics Center is outstanding and the greater community at Einstein offers opportunities for collaborations on a number of shared projects. Enthusiastic and highly motivated candidates are encouraged to contact Dr. Robert Coleman by e-mail at robert.coleman2@einstein.yu.edu with a CV, a description of research interests and at least three references.